Notes/Biology/Paper 1/Sexual Reproduction in Humans
CAIEO Level5090§16.4

Sexual Reproduction in Humans

The male and female reproductive systems; sperm and egg cells and fertilisation; puberty; the menstrual cycle and the four hormones that control it; the journey from ovulation to implantation; and how the fetus is protected by the amniotic sac and fed through the placenta and umbilical cord.

170 min read 10 sub-topics
48
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2021–2025 · 20 papers
4 marks
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≈ 3% of the paper
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#18
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of 22 topics by marks

In the last chapter you saw how flowering plants reproduce sexually: pollen carries the male gamete to the female gamete, and fertilisation makes a seed. Humans also reproduce sexually, but the gametes meet inside the woman's body, and the baby grows there too.

We start with the organs of the male and female reproductive systems, then the two gametes, sperm and egg cells, and how each is suited to its job. Next come the changes of puberty and the monthly menstrual cycle with the four hormones that control it. Last, we follow a fertilised egg as it becomes a ball of cells, settles into the uterus, and grows into a fetus fed through the placenta. By the end you can label both systems, read menstrual-cycle graphs, and explain what crosses the placenta and why.

Before you start you should be able to
  • Gametes are haploid and are made by meiosis; at fertilisation two haploid nuclei fuse to form a diploid zygote, which divides by mitosis (Cell Division and Reproduction)

  • A hormone is a chemical made by an endocrine gland and carried in the blood to a target organ; the pituitary gland is in the brain (Coordination and Control)

  • Diffusion is the net movement of particles down a concentration gradient (Movement Into and Out of Cells)

  • Mitochondria release energy by aerobic respiration; enzymes are proteins that speed up reactions (Cell Structure and Organisation, Enzymes)

  • Antibodies are made by lymphocytes; passive immunity is getting antibodies made by another person (Disease and Immunity)

By the end of this page you can
  • Identify the testes, scrotum, sperm ducts, prostate gland, urethra and penis on diagrams of the male reproductive system, and describe their functions

  • Identify the ovaries, oviducts, uterus, cervix and vagina on diagrams of the female reproductive system, and describe their functions

  • Explain how the flagellum, mitochondria and acrosome enzymes of a sperm cell, and the energy stores and jelly coat of an egg cell, are related to their functions

  • Describe fertilisation as the fusion of the nuclei from a sperm and an egg cell, and compare the two gametes in size, structure, numbers and motility

  • Describe the roles of testosterone and oestrogen in the development and regulation of secondary sexual characteristics during puberty

  • Describe the menstrual cycle in terms of the development and release of an egg and the changes in the uterus lining, and read cycle diagrams and graphs

  • Explain the roles of FSH, LH, oestrogen and progesterone in controlling the menstrual cycle, including in pregnancy

  • Trace the route of sperm to the oviduct, and describe how the zygote forms a ball of cells (embryo) that implants in the uterus lining

  • State the functions of the amniotic sac and amniotic fluid

  • Identify the placenta and umbilical cord, describe the exchange of dissolved nutrients, gases and excretory products between the mother's blood and the fetus's blood, and state that some viruses can cross the placenta

01

The male reproductive system

Syllabus requirement · §16.4.1

“

16.4.1 Identify, on diagrams of the male reproductive system: the testes, scrotum, sperm ducts, prostate gland, urethra and penis, and describe their functions.

”

The one sentence to carry

Sperm are made in the testes (which hang in the scrotum), travel up the sperm ducts, receive fluid from the prostate gland, and leave through the urethra in the penis.

Six structures, in the order sperm travel

A reproductive system is the group of organs that make gametes (sex cells) and bring them together. The male gametes are sperm.

StructureWhat it isFunction
Testes (one: testis)Two oval organsMake sperm (by meiosis). They also make the hormone testosterone
ScrotumA sac of skin that hangs outside the bodyHolds the testes outside the body, where it is slightly cooler — sperm are made best a little below body temperature
Sperm ductsTwo tubes, one from each testisCarry sperm from the testes to the urethra
Prostate glandA gland around the urethra, just below the bladderAdds a fluid to the sperm. The fluid contains nutrients, and the sperm swim in it
UrethraThe tube running through the penisCarries semen (sperm + fluid) out of the body. It also carries urine, but never at the same time
PenisThe organ containing the urethraPlaces semen (sperm) into the woman's vagina during sexual intercourse

Semen is the mixture of sperm and the fluid from the glands. Releasing semen from the penis is called ejaculation.

The pathway to learn

testis→sperm duct→urethra (in the penis)→out of the body\text{testis} \rightarrow \text{sperm duct} \rightarrow \text{urethra (in the penis)} \rightarrow \text{out of the body}

The sperm duct does not join the bladder. It joins the urethra, just below the bladder, where the prostate gland surrounds it. The bladder stores urine and is part of the urinary system (see Excretion), not the reproductive system. It is drawn on most diagrams only because it sits right next to the prostate gland.

Male reproductive system (side view)front of bodysperm ductcarries sperm to urethraurethracarries semen (and urine) outpenisplaces sperm in vaginabladderstores urine (not reproductive)prostate glandadds fluid for sperm to swim inscrotumholds testes outside body (cooler)testismakes sperm and testosterone

The male reproductive system, side view. Sperm are made in the testis, carried up the sperm duct, mixed with fluid from the prostate gland, and leave through the urethra in the penis. The bladder is part of the urinary system and is shown only to help you find your way.

Two mix-ups that lose marks

  • The prostate gland does not make sperm or testosterone. It makes the fluid the sperm swim in. Sperm and testosterone both come from the testes.
  • Sperm duct or urethra? The sperm duct carries only sperm, from a testis to the urethra (there are two). The urethra carries semen or urine out through the penis (there is one).
Worked example

Name the structure of the male reproductive system that does each job.

(a) makes sperm
(b) carries sperm from a testis towards the penis
(c) adds a fluid in which sperm can swim
(d) keeps the testes a little cooler than the rest of the body
(e) carries semen out of the body

Show full working
  1. 1

    (a) Sperm are made in the testes.

    The testes are the only place sperm are made. Every other structure only stores, carries or adds to them.

  2. 2

    (b) The tube from a testis is the sperm duct.

    There is one sperm duct from each testis. It leads up into the body and joins the urethra.

  3. 3

    (c) The fluid is added by the prostate gland.

    A gland makes and releases a substance. The prostate is the only gland on the syllabus list.

  4. 4

    (d) The scrotum holds the testes outside the body, where it is cooler.

    Sperm are made best slightly below normal body temperature, which is why the testes are not inside the body.

  5. 5

    (e) Semen leaves through the urethra, which runs along the penis.

    "Carries out of the body" is the urethra. The penis is the organ; the urethra is the tube inside it.

Answer

(a) testes; (b) sperm duct; (c) prostate gland; (d) scrotum; (e) urethra.

Learn each structure as a pair: name + one job. "Testis — makes sperm", "sperm duct — carries sperm", "prostate — fluid to swim in".

Worked example5090/11 M/J 2025 Q341 mark

What is the main function of the prostate gland?

Options

A   producing adrenaline
B   producing testosterone
C   producing a liquid in which the sperm can swim
D   storing mature sperm cells

Show full working
  1. 1

    The prostate gland adds a fluid to the sperm. The sperm swim in this fluid. So C is correct.

    This is the prostate's job in the table above, almost word for word.

  2. 2

    A is wrong: adrenaline is made by the adrenal glands (see Coordination and Control).

    Adrenaline has nothing to do with reproduction. It is a distractor from the hormones chapter.

  3. 3

    B is wrong: testosterone is made by the testes, not the prostate gland.

    This is the most tempting wrong answer, because both the prostate gland and testosterone are "male".

  4. 4

    D is wrong: the prostate gland does not store sperm. Sperm pass through the urethra next to it, but they are not kept there.

    "Storing" is a job that does not belong to any structure on the syllabus list.

Answer

C

Prostate = fluid for sperm to swim in. Testes = sperm and testosterone.

Worked example5090/11 M/J 2024 Q311 mark

What is the path taken by sperm cells during ejaculation from the male reproductive system?

Options

A   sperm duct → testis → urethra
B   sperm duct → urethra → testis
C   testis → sperm duct → urethra
D   testis → urethra → sperm duct

Show full working
  1. 1

    Start where sperm are made: the testis. That rules out A and B, which start in the sperm duct.

    A path always starts where the thing is made.

  2. 2

    From the testis, sperm move up the sperm duct, and the sperm duct joins the urethra. So the order is testis → sperm duct → urethra: C.

    The sperm duct is the only tube leaving a testis.

  3. 3

    D is wrong: it puts the urethra before the sperm duct, and it ends in the sperm duct, which does not lead out of the body.

    The last structure must be the urethra, because it is the only tube that opens to the outside.

Answer

C

Testis → sperm duct → urethra. The same question has been set in several years.

Worked example5090/12 M/J 2022 Q341 mark

The diagram shows the human male reproductive system.

Which structure may contain sperm?

Options

A   A
B   B
C   C
D   D

The diagram, as printed with the question.

The diagram, as printed with the question.

Show full working
  1. 1

    Sperm are found only in the testes and in the tubes they travel along: the sperm ducts and the urethra. So look for a label on one of those.

    Turn "may contain sperm" into a short list of possible structures before looking at the letters.

  2. 2

    A labels the large sac at the top: the bladder. It holds urine, not sperm.

    The bladder sits at the top of a side view, with a ureter entering it from above.

  3. 3

    B and C label the glands near the bottom of the bladder. Glands add fluid to the sperm; they are not the tubes the sperm travel in.

    The grey gland wrapped around the tube just under the bladder is the prostate gland.

  4. 4

    D labels the tube running along the inside of the penis: the urethra. Sperm pass through it during ejaculation. So D is correct.

    The urethra carries semen, which contains sperm, out of the body.

Answer

D

On a side view, find the bladder first (top), then the tube leaving it (urethra), then trace back from the testis (sperm duct).

Your turn

  1. 12 marks

    State the function of (a) the scrotum and (b) the penis.

    Show solution
    1. 1

      (a) The scrotum holds the testes outside the body, where the temperature is slightly lower.

      Say where it holds the testes and why that matters: sperm are made best a little below body temperature.

    2. 2

      (b) The penis places semen (sperm) into the vagina during sexual intercourse.

      The penis contains the urethra, but its own job is to deliver the sperm into the woman's body.

    Answer

    (a) It holds the testes outside the body, keeping them slightly cooler than body temperature, which is best for making sperm. (b) It places semen (containing sperm) into the vagina during sexual intercourse.

  2. 22 marks

    A student writes: "Sperm are made in the prostate gland and then pass into the bladder." Correct both mistakes.

    Show solution
    1. 1

      Sperm are made in the testes, not the prostate gland. The prostate gland adds a fluid for the sperm to swim in.

      Give the correct organ and say what the prostate really does.

    2. 2

      Sperm pass along the sperm duct into the urethra, not into the bladder. The bladder stores urine.

      The sperm duct joins the urethra just below the bladder.

    Answer

    Sperm are made in the testes (the prostate gland only adds fluid). They travel along the sperm ducts into the urethra; they never enter the bladder, which stores urine.

  3. 35090/12 O/N 2016 Q351 mark

    The diagram shows part of the male reproductive and urinary systems.

    What is X?

    Options

    A   prostate gland
    B   sperm duct
    C   ureter
    D   urethra

    The diagram, as printed with the question.

    The diagram, as printed with the question.

    Stuck? Show hint

    Follow the tube labelled X. Where does it start and where does it end?

    Show solution
    1. 1

      X is a tube running along the length of the penis to its tip.

      Look at where the label line touches, then follow the tube both ways.

    2. 2

      The tube inside the penis that opens to the outside is the urethra. So D.

      The urethra carries urine or semen out of the body.

    3. 3

      A is wrong: the prostate gland is the round, cross-hatched gland just below the bladder. B is wrong: the sperm duct runs from the testis up into the body. C is wrong: the ureter enters the top of the bladder from the kidney.

      Each wrong option is a real structure on the diagram, just in a different place.

    Answer

    D

The rest of this note

Checking your access…

Can you do all of these?

  • Identify the testes, scrotum, sperm ducts, prostate gland, urethra and penis on a side-view diagram, and state the function of each

  • Identify the ovaries, oviducts, uterus, cervix and vagina on front and side views, and state the function of each

  • Explain how the flagellum, mitochondria and acrosome help a sperm, and how energy stores and the jelly coat help an egg

  • Define fertilisation as the fusion of the nuclei of a sperm and an egg, and compare sperm and eggs in size, structure, numbers and motility

  • State that testosterone (testes) and oestrogen (ovaries) cause and maintain the secondary sexual characteristics, and name examples of each

  • Describe the 28-day menstrual cycle: menstruation, repair of the lining, ovulation at about day 14, lining kept thick; find these on circles, calendars and lining graphs

  • Explain the jobs of FSH, LH, oestrogen and progesterone, identify each on a hormone graph, and predict their levels in pregnancy

  • Give the route of sperm to the oviduct, and describe fertilisation in the oviduct, mitosis to a ball of cells, and implantation in the uterus lining

  • State that amniotic fluid, held in the amniotic sac, protects the fetus from mechanical shock

  • Identify the placenta and umbilical cord, state what diffuses in each direction, compare the umbilical artery and vein, explain why the bloods do not mix, and state that some viruses (such as HIV) can cross the placenta